PUDMED DE YER ALAN ULUSLARARASI DERGİLERDE BASILMIŞ YAYINLARI:
https://pubmed.ncbi.nlm.nih.gov/?term=Kutukculer
1992 – 2010 Arası Yayınlar
1-Mir S, Kütükçüler N, Cura A. Use of single voided urine samples to estimate quantitative proteinuria in children. Turkish Journal of Pediatrics 34(4): 219-225, 1992.
2-Mir S, Kütükçüler N, Kavaklı K. Major histocompatibility complex antigens in Turkish children with steroid-responsive nephrotic syndrome ( let ). Pediatric Nephrology 8 : 259-260, 1994.
3-Mir S, Kütükçüler N, Kavaklı K. Major Histocompatibility complex antigens and immune mechanisms in steroid-responsive nephrotic syndrome. Acta Pediatrica japonica 36 (6) : 662-665, 1994.
4-Mir S, Kütükçüler N, Çoker M, Keskinoğlu A. Major histocompatibility complex antigens in Turkish children with Henoch-Schonlein purpura ( let ). Nephrology, dialysis,Transplantatıon 9 (5): 586-587, 1994.
5-Kültürsay N, Kütükçüler N, Büyükgebiz B, Kleijer WJ. A case of maple syrup urine
disease misdiagnosed as tetanus neonatorum on admission. Acta Pediatrica Japonica 36:284-286, 1994.
6-Kültürsay N, Köprübaşı F, Kütükçüler N. Video display terminal- the risk of Trisomy
18? (let) Clinical Genetics, 45 (5) : 270-271, 1994.
7–Kütükçüler N, Shenton BK, Clark K, Rigg KM, Forsythe JLR, Kirby JA, Proud G, Taylor RMR. Renal allograft rejectıon: The temporal relationship and predictive value of plasma TNF (alpha and beta), IFN-gamma and soluble ICAM-1. Tranplant International 8 ( 1 ) : 45-50, 1995.
8-Kütükçüler N, Shenton BK, Clark K, Rigg KM, Forsythe JLR, Proud G, Taylor RMR. The value of post-transplant monitoring of IL-2,IL-3,IL-4,IL-6,IL-8 and soluble CD23 in the plasma of renal allograft recipients. Tranplantation 59 (3) : 333-340, 1995.
9-Narin N, Kütükçüler N, Özyürek R, Bakiler AR, Parlar A, Arcasoy M. Lymhocyte subsets and plasma IL-1 alfa, IL-2 and TNF-alfa concentrations in acute rheumatic fever and cronic rheumatic heart diseases. Clinical Immunology and Immunopathology 77 (2): 172- 176, 1995.
10–Kütükçüler N, Özdoğru E, Demir E, Tanaç R. Plasma Interleukin-3 and Interleukin-4 concentrations in Turkish Asthmatic Children (let). Archives of Diseases in Childhood 73: 378-379, 1995.
11–Kütükçüler N, Narin N. Plasma interleukin-7 (IL-7) and IL-8 concentrations in acute rheumatic fever and chronic rheumatic heart disease. Scandinavian Journal of Rheumatology 24 : 383-385, 1995.
12–Kütükçüler N, Kutlu O, Nişli G, Öztop S, Çetingül N, Çağlayan S. Assessment of
neutrophil chemotaxis and random migration in children with thalassemia major. Pediatric Hematology and Oncology 13 : 239-245, 1996.
13–Kütükçüler N, Kurugöl Z, Egemen A, yenigün A, Vardar F. The effect of immunization against tetanus during pregnancy for protective antibody titres and specific antibody responses of infants. Journal of Tropical Pediatrics 42 : 308-309, 1996.
14-Narin N,Kütükçüler N, Narin F, Keser G,Doğanavşargil E. Anticardiolipin antibodies in acute rheumatic fever and chronic rheumatic heart disease : is there a significant assocition ?. Clinical and Experimental Rheumatology 14: 567-569, 1996.
15–Kütükçüler N, Yagci RV. Our experience in Reye’s Syndrome. Journal of Pediatric Gastroenterology and Nutrition 23 (3) : 338-339, 1996.
16–Kütükçüler N, Vergin C, Kavaklı K, Çetingül N, Öztop S, Nişli G, Çağlayan S. Specific antibody response in children with thalassemia major. Pediatric Hematology and Oncology 14 : 181-183, 1997.
17-Vergin C, Kütükçüler N, Çetingül N, Nişli G, Çağlayan S, Öztop S. Serum immunoglobulins,IgG subclasses, isohemagglutinins and complement-3 levels in patients with thalassemia mojor. Indian Journal of Pediatrics 64: 215-219, 1997
18-Kütükçüler N, Aydoğdu S, Göksen D, Çağlayan S, Yağcı RV. Increased mucosal inflammatory cytokines in children with Helicobacter pylori-associated gastritis. Acta Pediatrica 86: 928-931, 1997.
19-Kütükçüler N, Çağlayan S. Tumor necrosis factor-a and interleukin-6 in stools of children with bacterial and viral gastroenteritis. Journal of Pediatric Gastroenterology and Nutrition 25: 556-557, 1997.
20-Çetingül N, Kütükçüler N, Kantar M, Kavaklı K, Nişli G, Çağlayan S, Öztop S. Recombinant Human Granulocyte -macrophage colony-stimulating factor therapy and endogenous plasma GM-CSF, IL-3, IL-4 concentrations in Pediatric Patients with solid tumors. Turkish Journal of Pediatrics 39 (4): 473-481, 1997.
21– Kurugöl Z, Egemen A, Erensoy S, Bilgiç A, Kütükçüler N. Intradermal administration of hepatitis-B vaccine in infants and preschool children. Turkish Journal of Pediatrics 39 (4): 483-489, 1997.
22-Kütükçüler N, Vergin C, Çetingül N, Kavaklı K, Çağlayan S, Öztop S, Nişli G. Plasma Interleukin-3 (IL-3) and IL-7 concentrations in children with homozygous beta-thalassemia. Journal of Tropical Pediatrics 43: 366-67, 1997.
23-Kütükçüler N, Tütüncüoğlu S, Yılmaz D, Akalın T, Kandiloğlu G. Subcutaneous granuloma annulare and IgA-IgG2 deficiency. Turkish Journal of Pediatrics 40: 279-282, 1998.
24-Kütükçüler N, Çağlayan S. Plasma and synovial fluid soluble CD23 concentrations in children with juvenile chronic arthritis. Autoimmunity 27:155-158, 1998.
25- Atilla G, Kütükçüler N. Crevicular fluid ınterleukin-1 b, tumor necrosis factor-a and interleukin-6 levels in renal transplant patients receiving cyclosporine A. Journal of Periodontology 69: 784-790, 1998.
26- Kütükçüler N, Aydoğdu S, Çağlayan S, Yağcı RV. Salivary and gastric fluid secretory Immunoglobulin A and free secretory component concentrations in children with Helicobacter pylori-positive gastritis. Journal of Tropical Pediatrics 44:178-180, 1998.
27-Kutukculer N, Cağlayan S, Aydoğdu F. Study of pro-inflammatory (TNF-alpha, IL-1 alpha, IL-6) and T cell-derived (IL-2, IL-4) cytokines in plasma and synovial fluid of patients with juvenile Chronic arthritis : Correlations with Clinical and laboratory parameters. Clinical Rheumatology 17: 288-292, 1998.
28- Tekgül H, Kütükçüler N, Çağlayan S, Tütüncüoğlu S. Pro-inflammatory cytokines, lymphocyte subsets and intvenous immunoglobulin therapy in Guillain Barre syndrome. Turkish Journal of Pediatrics 40: 357-363, 1998.
29- Kavaklı K, Nişli G, Kütükçüler N, Polat A, Aydınok y, Öztop S, Çetingül N. Long term prophylaxis and immune parameters in Haemophilia. Journal of Tropical Pediatrics 45:122-123, 1999.
30- Hüseyinov A, Kütükçüler N, Aydoğdu S, Çağlayan S, Çoker I, Gökşen D, Yağcı RV. Increased Gastric Production of Platelet-Activating Factor, Leukotriene-B4 and Tumor Necrosis Factor-alpha in Children with Helicobacter Pylori Infection. Digestive Disease and Sciences 44(4): 675-678, 1999.
31- Tekgül H, Tutuncuoğlu S, Kutukculer N, Dizdarer G, Huseyinov A. Lymphocyte Subsets and Inflammatory Mediators in Patients with Subacute Sclerosing Panencephalitis. Journal of Child Neurology 14: 418-421, 1999.
32-Kantar M, Kültürsay N, Kütükçüler N, Akisu M, Çetingül N, Çağlayan S. Plasma concentrations of granulocyte-macrophage colony-stimulating factor and interleukin-6 in septic and healthy preterms. European Journal of Pediatrics 2000; 159: 157-157.
33-Kütükçüler N, Akil T, kurugöl Z, et al. Adequate immune response to tetanus toxoid and failure of vitamin A and E supplementation to enhance antibody response in healthy children. Vaccine 2000 ;18(26): 2979-2984.
34-Kutukculer N, Aksu G. Is there an association between autoimmune hemolytic anemia and ataxia-telengiectasia ? Autoimmunity 32: 145-147, 2000.
35–Kütükçüler N, Yağcı RV, Aydoğdu S, Aksu G, Genç B. Chronic inflammatory bowel disease in a patient with common variable immunodeficiency. The Turkish Journal of Pediatrics 2001: 43; 88-90.
36– Buduneli N, Kutukçüler N, Aksu G, Atilla G. Evaluation of transforming growth factor-beta1 level in crevicular fluid of cyclosporin A-treated patients. Journal of Periodontology 2001; 72(4): 526-531.
37-Buduneli N, Baylas H, Aksu G, Kütükçüler N. Prepubertal periodontitis associated with chronic granulomatous disease. Journal of Clinical Periodontology 2001; 28(6): 589-93.
38–Aksu G, Tirpan C, Cavusoglu C, Soydan S, Altare F, Casanova JL, Kutukculer N. Mycobacterium fortuitum-chelonae complex infection in a child with complete interleukin-12 receptor beta 1 deficiency. Pediatr Infect Dis J. 2001 May;20(5):551-3.
39-Kurugol Z, Özkınay F, Vardar F, Karacaali S, Kutukculer N, Deveci R. Gricelli syndrome: Report of a case and review of the literature. Pediatrics International 2001; (43(3) : 298-301.
40-Tütüncüoğlu S, Kütükçüler N, Kepe L, Çoker C, Berdeli A, Tekgül H. Proinflammatory cytokines, prostaglandins and zinc in febrile convulsions. Pediatrics International 2001; 43 (3): 235-239.
41-Emingil G, Darcan S, Keskinoğlu A, Kütükçüler N, Atilla G. Localized aggressive periodontitis in a patient with Type 1 Diabetes Mellitus: A case report. Journal of Periodontology 2001; 72: 1265-1270.
42– Genel F, Erermiş S, Aksu G, Ozturk C, Kutukculer N. Quinacrine-induced psychiatric disturbances in a child with common variable immunodeficiency and chronic giardiasis. Human Psychopharmacology (Hum Psycopharmacol Clin Exp) 2002; 17: 357-359.
43–Kutukculer N, Aksu G, Genel F, Ozturk C. Idiopathic CD4+ T cell lymphocytopenia with the absence of B cells and CD8+28+ cells in peripheral blood. Clinical and Experimental Medicine 2002; 2: 143-146.
44- F.Unal, F.Genel, F.Özgenç, G.Aksu, S.Aydoğdu, N.Kutukculer, RV.Yagcı. Immune status and autoantibody formation in children with chronic hepatitis B infection. Panminerva Medica 2002; 44: 353-357.
45- Tanaç R, Demir E, Aksu G, Sarı G, Kutukculer N. Effect of immunotherapy on autoimmune parameters in children with atopic asthma. Turkish Journal of Pediatrics 2002; 44; 294-297.
46- Aksu G, Kutukculer N, Genel F, Vergin C, Omowaire B. Griscelli Syndrome without hemophagocytosis in an eleven-year-old girl. Expanding the phenotypic spectrum of Rab27A mutations in Humans. American Journal of Medical Genetics 2003; 116A: 329-333.
47– Kutukculer N, Moratto D, Aydınok Y, Lougaris V, Aksoylar S, Plebani A, Genel F, Notarangelo LD. Disseminated cryptosporidium infection in an infant with Hyper-IgM syndrome caused by CD40 deficiency. Journal of Pediatrics 2003; 142: 194-196.
48-Fieschi C, Dupuis S, Aksu G, Kutukculer N, Casanova JL, et al. Low penetrance, broad resistance and favorable outcome of IL-12 receptor beta-1 deficiency: Medical and immunological implications. Journal of Experimental Medicine 2003; 197; 527-535.
49-Genel F, Unal F, Özgenç F, Aksu G, Aydogdu S, Kutukculer N, Rasit V. Yagcı. Decreased ratio of CD4/CD8 lymphocytes might be predictive for successful interferon alpha and lamivudine combined therapy in childhood chronic hepatitis B infection: A preliminary study. Journal of Gastroenterology and Hepatology 2003; 18: 645-650.
50- Eralp Buduneli, Ferah genel, Gül Atilla, Necil Kütükçüler. Evaluation of p53, bcl-2 and interleukin-15 levels in gingival crevicular fluid of cyclosporin A-treated patients. Journal of Periodontology 2003: 74: 506-511.
51-Özgenç F, Aksu G, Aydogdu S, Akman S, Genel F, Kutukculer N, Alkanat MB, Yagcı R. Association between anti-endomysial antibody and total intestinal villous atrophy in children with coeliac disease. Jounal of Postgraduate Medicine, 2003: 49; 21-24.
52-Akısu M, Yalaz M, Arslanoglu S, Genel F, Kutukculer N, Kültürsay N. Maternally acquired varicella-zoster virus antibodies disappear at 6 months of age in prematurely born children. Panminerva Med 2003: 45; 155-156.
53-Fontana S, Moratto D, Mangal S, De Francesco M, Vermi W, Ferrari S, Fachetti F, Kutukculer N, et al. Functional defects of dendritic cells in CD40-deficient patients. Blood 2003; 102(12): 4099-4106.
54-Cogulu O, Ozkınay F, Gunduz C, Cankaya T, Aydogdu S, Özgenc F, Kutukculer N, Ozkınay C. Celiac Disease in children with Down syndrome: importance of follow-up and serologic screening. Pediatrics International 2003; 45: 395-99.
55–Kutukculer N, Aksoylar S, Kansoy S, Cetingul N, Notarangelo LD. Outcome of hematopoietic stem cell transplantation in Hyper-IgM syndrome caused by CD40 deficiency. Journal of Pediatrics 2003; 143: 141-142.
56- Kantar M, Çetingül N, Kansoy S, Kutukculer N, Aksu G. İmmune deficiencies following cancer treatment in children. Journal of Tropical Pediatrics 2003; 49 (5): 286-290.
57-Genel F, Kutukculer N. Prospective, randomized comparison of OM-85 BV and a prophylactic antibiotic in children with recurrent infections and Immunoglobulin A and/or G subclass deficiency. Current Therapeutic Research Clin Exp 2003; 64(8): 600-615.
58-Büyükyazı G, Kutukculer N, Kutlu N, Genel F, Karadeniz G, Özkütük N. Differences in the cellular and humoral immune system between idle-aged man with different intensity and duration physically training. J Sports Med Phys Fitness 2004; 44: 207-214.
59– Tekgül H, Polat M, serdaroğlu G, İkizoğlu T, Yalaz M, Kutukculer N, Gökben S. Lymphocyte subsets in bell’s palsy: Immune Pathogenesis and outcome prediction. Pediatric Neurology 2004; 31(4): 258-60.
60-Tekgul H, Yalaz M, Kutukculer N, Ozbek S, Kose T, Akisu M, Kültürsay N, Gokben S. Value of biochemical markers for outcome in term infants with asphyxia. Pediatric Neurology 2004; 31(5): 326-332.
61- Kutukculer N, Yuksek SE, Aksu G, Alper S. Autoantibodies other than antineutrophil cytoplasmic antibodies are not positive in patients with psoriasis vulgaris. The journal of Dermatology 2005; 32: 179-185.
62-Tekgül H, Polat M, Kütükçüler N, et al. T cell subsets and interleukin-6 response in Rasmussen’s encephalitis. Pediatric Neurology 2005; 33(1): 39-45.
63-Balkan C, Kavaklı K, Kutukculer N, Aksu G, Yılmaz D, Aydınok Y. The effect of clotting factor concentrates on the immune system in HIV-negative haemophiliacs. Haemophilia 2005; 11(4): 366-70.
64-Aksu G, Bayram N, Ulger Z, Öztürk C, Ozyurek AR, Bakiler AR, Kutukculer N. Inverse relationship between the ratio of ICAM-1 expressing lymphocytes and serum TGF-beta1 concentrations in acute rheumatic fever. J Autoimmune 2005; 25: 141-149.
65-Cogulu D, Sabah E, Kutukculer N, Ozkinay F. Evaluation of the relationship between caries indices and salivary IgA, salivary pH, buffering capacity and flow rate in children with Down’s syndrome. Arch Oral Biol 2006;51: 23-28
66-Tekgul H, Polat M, Tosun A, Serdaroğlu G, Kütükçüler N, Gokben S. Cerebrospinal fluid IL-6 levels in patients with west syndrome. Brain & Development 2006; 28:19-23.
67-Aksu G, Genel F, Koturoğlu G, Kurugöl Z, Kütükçüler N. Serum immunoglobulin (IgG,IgA,IgM) and IgG subclass concentrations in healthy children: a study using nephelometric technique. Turk J Pediatr 2006; 47: 19-24
68- Öztürk C, Aksu G, Berdeli A, Kütükçüler N. Fc gamma RIIa, IIIa and IIIb polymorphism in Turkish Children susceptible to recurrent infectious diseases. Clin Exp Med 2006; 6; 27-32.
69- Ozgenc F, Aksu G, Kirkpinar F, Altuglu I, Coker I, Kutukculer N, Yagci RV . The influence of marginal zinc deficient diet on post-vaccination immune response against hepatitis B in rats. Hepatol Res. 2006 ; 35: 26-30.
70– Kutukculer N, Genel F, Aksu G, Karapinar B, Ozturk C, Cavusoglu C, Casanova JL, Fieschi C. Cutaneous leukocytoclastic vasculitis in a child with interleukin-12 receptor beta-1 deficiency. J Pediatr. 2006 Mar;148(3):407-9.
71- Aksu G, Ozturk C, Kavakli K, Genel F, Kutukculer N.
Hypercoagulability: interaction between inflammation and coagulation in familial Mediterranean fever. Clin Rheumatol. 2007; 26; 366-70.
72- Filipe-Santos O, Bustamante J, Haverkamp MH, Vinolo E, Ku CL, Puel A, Frucht DM, Christel K, von Bernuth H, Jouanguy E, Feinberg J, Durandy A, Senechal B, Chapgier A, Vogt G, de Beaucoudrey L, Fieschi C, Picard C, Garfa M, Chemli J, Bejaoui M, Tsolia MN, Kutukculer N, Plebani A, Notarangelo L, Bodemer C, Geissmann F, Israel A, Veron M, Knackstedt M, Barbouche R, Abel L, Magdorf K, Gendrel D, Agou F, Holland SM, Casanova JL. X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production. J Exp Med. 2006 Jul 10;203(7):1745-59.
73– Biyikoglu B, Buduneli N, Kardesler L, Aksu K, Oder G, Kutukculer N. Evaluation of t-PA, PAI-2, IL-1beta and PGE in gingival crevicular fluid of rheumatoid arthritis patients with periodontal disease. J Clin Periodontol. 2006 ; 33: 605-611.
74-Edeer Karaca N, Aksu G, Yeniay BS, Kutukculer N. Juvenile dermatomyositis with a rare and remarkable complication: sinus bradycardia. Rheumatol Int 2006; 27: 179-182.
75-Kansoy S, Kütükçüler N, Aksoylar S, Aksu G, Kantar M, Çetingül N. Succesful bone marrow transplantation in an 8-month old patient with chronic granulamatous disease. Turk J Pediatr 2006; 48: 253-55.
76– Buduneli N, Coğulu D, Kardeşler L, Kutukculer N. Dental findings and treatment in consanguinity associated congenital chronic familial neutropenia. J Clin Pediatr Dent 2006; 31: 123-6.
77–Kutukculer N, Edeer Karaca N, Demircioglu O, Aksu G. Increases in serum immunoglobulins to age related normal levels in children with IgA ana/or IgG subclass deficiency. Pediatr Allergy Immunol 2007; 18; 167-73.
78- Cogulu O, Aykut A, Kutukculer N, Ozkınay C, Ozkınay F. Two cases of macrocephaly and immune deficiency. Clinical Dysmorphology 2007; 16: 81-84.
79-Yeniay BS, Karaca NE, Yüksel SE, Midyat L, Kütükçüler N. Juvenile psoriatic arthritis carrying familial Mediterrenean gene mutations in a fourteen years old Turkish girl. Journal of Dermatology 2007; 34: 344-48.
80- Mazzolari E, Lanzi G, Forino C, Lafranchi A, Aksu G, Öztürk C, Giliani S, Noarangelo LD, Kutukculer N. First report of successful stem cell transplantation in a child with CD40 deficiency. Bone Marrow Transplant 2007 ; 40: 279-281.
81-Bustamante J, Aksu G, Vogt G, Genel F, Kutukculer N, casanova JL. BCG-osis ve tuberculosis in a child with chronic granulomatous disease. J Allergy Clin Immunol 2007; 120: 32-38.
82–Kutukculer N, Yeniay BS, Aksu G, Berdeli A. Arg753Gln Polymorphism of the human Toll-like receptor-2 gene in children with recurrent febrile infections. Biochem Genet 2007: 45: 507-514.
83-Çoğulu D, Oncağ O, Kütükçüler N, Uzal A, Eronat C. The correlation between serum Iimmunoglobulin A ana ımmunoglobulin G levels ana the presence of Treponema denticola in human periapical lesions. J Endodonty 2007; 33: 1413-6.
84– Arıkan F, Buduneli N, Kütükçüler N. Osteoprotegerin levels in peri-implant crevicular fluid. Clin Oral Implants Res 2008; 19: 283-288.
85-Türkoğlu O, Barış N, Kütükçüler N, Senarslan O, Güneri S, Atilla G. Evaluation of serum anti-cardiolipin ana oxidized low-density lipoprotein levels in chronic periodontitis patients with essential hypertension. J Periodontol 2008; 79: 332-340.
86–Kütükçüler N, Karaca NE, Sözeri BY, Koturoglu G, Kurugöl Z, Özyürek R, Aksu G: Human soluble tumor necrosis factor receptor I (sTNF-RI) ana interleukin-I receptor antagonist (IL-1RA) in different stages of acute rheumatic fever. Anadolu Kardiyol Derg 2008; 8: 139-42.
87-Kardeşler L, Buduneli N, Bıyıkoğlu B, çetinkalp Ş, Kütükçüler N. Gingival crevicular fluid PGE2, IL-1B, t-PA, PAI-2 levels in type-2 diabetes ana relationship with periodontal disease. Clinical Biochemistry 2008; 41: 863-68.
88-Aksu G, Kalkan US, Bulut Y, Kutukculer N. Renal involvement as a rare complication of Dorfman-Chanarin Syndrome: A case report. Pediatric Dermatology 2008; 25: 326-31.
89-Gülez N, Karaca NE, Aksu G, Kutukculer N. Increased percentages of autoantibodies in Immunoglobulin A-deficient children do not correlate with clinical manifestations. Autoimmunity 2009; 42: 74-79.
90-Turkoğlu O, Becerik S, Emingil G, Kütükçüler N, Baylas H, Atilla G. The effect of adjunctive chlorhexidine mouthrinse on clinical parameters and gingival crevicular fluid cytokine levels in untreated plaque-associated gingivitis. Inflammation Research 2009; 58: 1-7.
91–Kutukculer N, Gülez N. The outcome of patients with unclassified hypogammaglobulinemia in early childhood. Pediatr Allergy Immunol 2009; 20: 693-98.
92-Karaca NE, Aksu G, Yildiz B, Gulez N, Turk B, Dereli T, Kutukculer N. Relapsing ploychondritis in a child with common variable immunodeficiency. Int J Dermatol 2009; 48(5) : 525-8.
93-Karaca NE, Aksu G, Genel F, gülez N, Can S, Aydınok Y, Aksoylar S, Karaca E, Altuglu I, Kutukculer N. Diverse phenotypic ana genotypic presentation of RAG1 mutations in two cases with SCID. Clin Exp Med 2009; 9: 339-42.
94-Türkoğlu O, Emingil G, Kütükçüler N, Atilla G. Gingival Crevicular Fluid Levels of Cathelicidin LL-37 and Interleukin-18 in Patients With Chronic Periodontitis. J Periodontol. 2009 Jun;80(6):969-76.
95-Karaca NE, Karadeniz C, Aksu G, Kutukculer N. Clinical and laboratory evaluation of periodically monitored Turkish children with IgG subclass deficiency. Asian Pac J Allergy Immunol 2009; 27(1): 43-8.
96– Khatib SA, Keles S, Garcia-Lloret M, Karakoc-Aydiner E, Reisli I, Artac H, Camcioglu Y, Cokugras H, Somer A, Kutukculer N, Yilmaz M, Ikinciogullari A, Yegin O, Yüksek M, Genel F, Kucukosmanoglu E, Baki A, Bahceciler NN, Rambhatla A, Nickerson DW, McGhee S, Barlan IB, Chatila T. Defects along the T(H)17 differentiation pathway underlie genetically distinct forms of the hyper IgE syndrome. J Allergy Clin Immunol 2009; July2
97-Buduneli N, Buduneli E, Kütükçüler N. Interleukin-17, RANKL ana osteoprotegerin levels in gingival crevicularfluid from smoking ana non-smoking patients with chronic periodontitis during initial Periodontal treatment. J periodontol 2009; 80: 1274-1280
98-Gürkan A, Emingil G, Nizam N, Doğanavşargil B, Sezak M, Kütükçüler N, Attilla G: Therapeutic efficacy of vasoactive intestinal peptide in Eschericha Coli lypopolysaccharide-induced experimental Periodontitis in rats. J Periodontol 2009; 80: 1655-64.
99–Kutukculer N, Gülez N, Karaca N, Aksu G, Berdeli A. A novel Y331X nonsense mutation in TNFRSF1A gene in two related Turkish families with periodic fever syndrome. Int J Immunogenet 2009; Oct 5 ; 102-5.
100– Gattman B, Grimbacher B, Beaute J, Dodoit Y, mahlaoui N, Fischer A, knerr V, Kindle G, Kutukculer N.the european internet-based patient ana research database for primary immunodeficiencies : results 2006-2008. Clin Exp Immunol 2009; 157: 3-11.
101–Engelhardt KR, McGhee S, Winkler S, Sassi A, Kutukculer N, et al. Large deletions ana point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of Hyper IgE syndrome. J Allergy Clin Immunol 2009; 124: 1289-302.
102-Türkoğlu O, Emingil G, Kütükçüler N, Atilla G. Evaluation o gingival crevicular fluid adrenomedullin ana human neutrophil peptide 1-3 levels of patients with different periodontal diseases. J Periodontol 2010; 2: 284-91.
103-Neslihan Edeer Karaca, Gülez N, Aksu G, Kütükçüler N. Common variable immunodeficiency: familial inheritance ana autoimmune manifestations in two siblings. Turk J Pediatr 2010; 52: 89-93.
104– Buduneli N, Buduneli E, Cetin EO, Kırılmaz L, Kütükçüler N Clinical findings and gingival crevicular fluid prostaglandin E2 and interleukin-1-beta levels following initial periodontal treatment and short-term meloxicam administration.. Expert Opin Pharmacother. 2010; 11: 1805-12.
105- Aksu G, Gulez N, Azarsiz E, Karaca N, Kutukculer N. Dtermination of cutt-off titres ana aggrement between immunofluorescence ana immunoblotting methods for detecting anti-nuclear antibodies in children. J Clin Lab Anal 2010; 24: 230-36.
106-Lanzi G, Ferrari S, Vihinen M, Caraffi S, Kutukculer N, Schiaffonati L, Plebani A, Notarangelo LD, Fra AM, Giliani S. Different molecular behavior of CD40 mutants causing hyper-IgM syndrome. Blood 2010: 116: 5867-5874.
107– Azarsız E, Gülez N, Karaca NE, Aksu G, Kutukculer N. Consanguinity rate and delay in diagnosis in Turkish patients with combined immunodeficiency: a single center study.. J Clin Immunol 2011; 31: 106-11
108- Karaca N, Aksu G, Ozturk C, Gulez N, Kutukculer N. Granulomatous pyoderma preceding chronic recurrent multifocal osteomyelitis triggered by vaccinations in a two-year-old boy: a case report. J Med Case Reports. 2010 Oct 18;4(1):325.
109-de Beaucoudrey L, Samarina A, Bustamante J, Cobat A, Boisson-Dupuis S, Feinberg , J, Al-Muhsen S, Jannière L, Rose Y, de Suremain M, Kong XF, Filipe-Santos O, Chapgier A, Picard C, Fischer A, Dogu F, Ikinciogullari A, Tanir G, Al-Hajjar S, Al-Jumaah S, Frayha HH, Alsum Z, Al-Ajaji S, Alangari A, Al-Ghonaium A, Adimi P, Mansouri D, Ben-Mustapha I, Yancoski J, Garty BZ, Rodriguez-Gallego C, Caragol I,Kutukculer N, Kumararatne. DS.
Revisiting Human IL-12Rβ1 Deficiency: A Survey of 141 Patients From 30 Countries. Medicine (Baltimore). 2010 Nov;89(6):381-402.
110- Karaca NE, Aksu G, Gulez N, Yildiz B, Azarsiz E, Kutukculer N.
New laboratory findings in Turkish patients with transient hypogammaglobulinemia of infancy.Iran J Allergy Asthma Immunol. 2010; 9(4): 237-43.
111– Gulácsy V, Freiberger T, Shcherbina A, Pac M, Chernyshova L, Avcin T, Kondratenko I, Kostyuchenko L, Prokofjeva T, Pasic S, Bernatowska E, Kutukculer N, Rascon J, Iagaru N, Mazza C, Tóth B, Erdős M, van der Burg M, Maródi L. Genetic characteristics of eighty-seven patients with the Wiskott-Aldrich syndrome. Mol Immunol 2011; 48: 788-92.
112- Karaca NE, Durandy A, Gulez N, Aksu G, Kutukculer N. Study of patients with Hyper IgM type IV phenotype who recovered spontaneously during late childhood and review of the literature. Eur J Pediatr 2011; 170 : 1039-1047
113-Atan Ö, Aksu G, Özgenç F, Akman SA, Karaca NE, Sertöz R, Yağcı RV, Kutukculer N. Determination of intracellüler Th1/Th2 type cytokines in lymphocytes of chronic hepatitis B patients treated with interferon-alpha. Turk J Gastroenterol 2010; 21: 401-10
2011 – 2025 Arası Yayınlar
114- Berdeli A, Mir S, Nalbantoglu S, Kutukculer N, Sozeri B, Kabasakal Y, Cam S, Solak M. Comprehensive Analysis of a Large-Scale Screen for MEFV Gene Mutations: Do They Truly Provide a “Heterozygote Advantage” in Turkey? Genet Test Mol Biomarkers. 2011; 15: 475-482.
115-Boisson DS, El BaghdadinJ, Parvaneh N, Bousfiha A, Bustamente J, Feiberg J, Samarina A, Kutukculer N, Casanova JL. IL-12Rbeta1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco ana Turkey. PLos One 2011; 6(4):e18524.
116-Nesrin Gülez, Güzide Aksu, Afig berdeli, Neslihan Karaca, Sema Tanrıverdi,
Necil Kutukculer, Elif Azarsiz. X-linked lymphoproliferative syndrome ana common variable immunodeficiency may not be differentiated by SH2D1A ana XIAP/BIRC4 genes sequence analysis. Case Reports in Medicine 2011; ID, 121258.
117– Kutukculer N, Karaca NE, Azarsız E, Aksu G, Gulez N. Immunoglobulin light chain levels can be used to determine disease stage in children with juvenile idiopathic arthritis. Clin Lab Science 2011; 24 (2): 93-98.
118– Karaca NE, Gulez N, Aksu G, Azarsiz E, Kutukculer N. Does OM-85BV prophylaxis trigger autoimmunity in IgA deficient children? International Immunoparmacology 2011; 11: 1747-1751.
119– Karaca NE, Aksu G, Karaca E, Tuzun F, Guneş AT, Özkınay F, Kutukculer N. Progressive morphea of early childhood tracing Blaschko’s lines on the face: Involvement of X chromosome monosomy in pathogenesis and clinical prognosis. Int J Dermatol 50: 1406-10, 2011.
120-Öztürk C, Halıcıoğlu O, Çoker I, Gulez N, Sutçuoglu S, Karaca N, Aksu G, Kutukculer N. Association of clinical ana genetical features in FMF with focus on MEFV strip assay sensitivity in 452 children from Western Anatolia, Turkey. Clin Rheumatol (C) 2012; 31: 493-501
121- Esther De Vries, Necil Kutukculer. Patient-centred screening for primary immunodeficiency, a multistage diagnostic protocol designed for non-immunologists: 2011 update. Clin Exp Immunol (B) 167; 109-119, 2012.
122-Sözeri B, Gülez N, Aksu G, Kutukculer N, Akalın T, Kandiloglu G. Pesticide-induced scleroderma and early intensive immunosuppressive treatment. Arch Environ Occup Health (C) 2012; 67: 43-47.
123-Gathmann B, Binder N, Ehl S, Kindle G, Kutukculer N. European Internet-based patient ana research database for primary immunodeficiencies. Clin Exp Immunol (B) 2012: 167; 479-91.
124-Kutukculer N, Gulez N, Karaca NE, Aksu G, Berdeli A. Novel mutations ana diverse clinical phenotypes in recombinase-activating gene 1 deficiency. Ital J Pediatr (B) 2012; 38: 8-15.
125-Karaca NE, Forveille M, Aksu G, Durandy A, Kutukculer N. Hyper-Immunoglobulin M syndrome type 3 with CD40 cell surface expression. Scand J Immunol (C) 2012; 76:21-25.
126-Jabara HH, McDonald DR, Janssen E, Massaad MJ, Ramesh N, Borzutzky A, Rauter I,Benson H, Schneider L, Baxi S, Recher M, Notarangelo LD, Wakim R, Dbaibo G,Dasouki M, Al-Herz W, Barlan I, Baris S, Kutukculer N, Ochs HD, Plebani A, Kanariou M, Lefranc G, Reisli I, Fitzgerald KA, Golenbock D, Manis J, Keles S,Ceja R, Chatila TA, Geha RS. DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nat Immunol (A). 2012; 13: 612-20.
127-Azarsız E, Ertam I, Karaca N, Aksu G, Alper S, Kutukculer N. IgG-anti-IgA antibodies: An autoimmune finding in patients with psoriasis vulgaris. Minerva Med (C) 2012; 103: 183-7.
128- Kutukculer N,Gülez N,Karaca NE, Aksu G, Berdeli A. Three different classifications, B lymphocyte subpopulations, TNFRSF13B (TACI), TNFRSF13C (BAFF-R), TNFSF13 (APRIL) gene mutations, CTLA-4 ana ICOS gene polymorphisms in Turkish Patients with Common variable immunodeficiency. J Clin Immunol (C) 2012;
129-Patel K, Akhter J, Kobynski L, Gathman B, Davis O, Kutukculer N, Sullivan KE: Immunoglobulin deficiencies: The B lymphocte side. Di George Syndrome. Journal of Pediatrics (A) 2012; July17..
130-Edeer-karaca N, Boisson dupuis S, Aksu G, Bustamente J, Kandiloglu G, Ozsan N, Hekimgil M, Casanova JL, Kutukculer N. Granulamatous skin lesions, severe scrotal and lower limb edema due to mycobacterial infections in a child with complete IFN-gamma R1 deficency. Immunotherapy (C) 2012; 4: 1121-7.
131- Kılıc SS, Özel M, Hafızoğlu D, Karaca NE, Aksu G, Kutukculer N. The prevalances and patient characteristics of primary Immunodeficiency diseases in Turkey-two centers study. J Clin Immunol (B) 2013;33:74-83
132– Wong GK, Goldacker S, Winterhalter C, Grimbacher B, Chapel H, Lucas M, Kutukculer N, et al. Outcomes of splenectomy in patients with common variable immunodeficiency (CVID); a survey of 45 patients. Clin Exp Immunol (B) 2013; 172: 63-72.
133– Moncada-Velez M, Bogunoviç D, Kong X, Tirpan C, Aksu G, Vincent Q, Kutukculer N, Casanova JL, Boisson-Dupuis S, et al. Partial IFN-gamma R2 deficiency is due to protein misfolding and can be rescued by inhibitors of glycosylation. Blood 2013; 122; 2309-2401.
134-Memmedova L, Azarsiz E, Karaca NE, Aksu G, Kutukculer N. Does intravenous immunoglobulin therapy prolong immunodeficiency in transient hypogammaglobulinemia of infancy? Pediatric Reports 2013; 5 :e-14-15
135-Qederni M, sanal O, İkincioğulları A, Tezcan I, doğu F, Sologuren I, Kutukculer N. Et al. Clinical features of candidiasis in patients with inherited interleukin-12 receptor Beta-1 deficiency. Clin Infect Dis 2014; 58: 204-213.
136-Gathmann B, Mahlaoui N, Oksendhendler H, Kutukculer N, et al. Clinical picture and treatment of 2212 patients with common variable immunodeficiency. J Allergy Clin Immunol (A) 2014;
137-Schatorje EJ, Gathmann B, Van Hout RW, de Vries E, Kutukculer N, et al. The PedPAD study: Boys predominate in the hypogammaglobulinemia registry of the ESID Online database. Clin Exp Immunol (A) 2014; 176(3): 187-93.
138- Gunaydın NC, Chou J, Karaca NE, Aksu G, Massad MJ, Azarsiz E, Ertan Y, Geha RS, Kutukculer N. A novel disease causing CD40L mutation reduces expression of CD40Ligand, but preserves CD40 binding capacity. Clin Immunol (A)2014; May 17;
139-Turkoğlu O, Azarsız E, Emingil G, Kutukculer N, Atilla G. Are proteinase 3 and cathepsine C enzymes related to pathogenesis of periodontitis? Biomed Res Int 2014: 420830
140– Azarsız E, Karaca NE, Günaydın NC, Gülez N, Öztürk C, Aksu G, Genel F, Kutukculer N. Do elevated serum IgM levels have to be included in probable diagnosis criteria of patients with ataxia-telangiectasia? Int J Immunopathol Pharmacol 2014; 27: 421-27.
141- Kracker S, Di Virgilio M, Forveille M, Durandy A, Kutukculer N, et al. An inherited immunglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex. JACI (J Clin Allergy Immunol) 2014; Oct 10. pii: S0091-6749(14)01205-6. doi: 10.1016/j.jaci.2014.08.030.
142- Grimbacher B, Kutukculer N, et al. European Society for Immunodeficiencies (ESID) registry 2014. Clin Exp Immunol 2014; 178: 18-20
143– Türkoğlu O, Gürkan A, Emingil G, Afacan B, Töz H, Kütükçüler N, Atilla G. Are anti-microbial peptides related to cyclosporine-A induced gingival overgrowth. Arch Oral Biol. 2015 ;60(3):508-515.
144–Aydin SE, Kilic SS, Aytekin C, Kumar A, Porras O, Kainulainen L, Kostyuchenko L, Genel F, Kütükcüler N, Karaca N, Gonzalez-Granado L. DOCK8 Deficiency: Clinical and Immunological Phenotype and Treatment Options – a Review of 136 Patients. J Clin Immunol 2015; Jan 28., 156:98-118
145-Turley AJ, gathmann B, bangs C, Bradbury M, Seneviratne S, Gonzales Li, Kutukculer N, et al. Spectrum and management of complement immunodeficiencies (excluding hereditary angioedema) across Europe. J Clin Immunol 2015, feb 8: 23:165-78.
146-Boisson-Dupuis S, Bustamante J, El-Baghdadi J, Camcioglu Y, Parvaneh N, El Azbaoui S, Agader A, Hassani A, El Hafidi N, Mrani NA, Jouhadi Z, Ailal F, Najib J, Reisli I, Zamani A, Yosunkaya S, Gulle-Girit S, Yildiran A, Cipe FE, Torun SH, Metin A, Atikan BY, Hatipoglu N, Aydogmus C, Kilic SS, Dogu F, Karaca N, Aksu G, Kutukculer N, Inherited and acquired immunodeficiencies underlying tuberculosis in childhood. Immunol Rev 2015; 264: 103-20.
147-The extended phenotype of 64 patients with dedicator of cytokinesis 8 deficiency. Engelhardt KR, Gertz ME, Keles S, Schäffer AA, Sigmund EC, Glocker C, Saghafi S, Pourpak Z, Ceja R, Sassi A, Graham LE, Massaad MJ, Mellouli F, Ben-Mustapha I, Khemiri M, Kilic SS, Etzioni A, Freeman AF, Thiel J, Schulze I, Al-Herz W, Metin A, Sanal Ö, Tezcan I, Yeganeh M, Niehues T, Dueckers G, Weinspach S, Patiroglu T, Unal E, Dasouki M, Yilmaz M, Genel F, Aytekin C,Kutukculer N,
JACI (Journal of Allergy and Clinical Immunology) 2015; 34: 118-34.
148- Coğulu D, Onay H, Özdemir Y, Aslan GI, Özkınay F, Kutukculer N, Eronat C. Associations of Interleukin (IL)-1beta,IL-1 receptor antagonists and IL-10 with dental carries. J Oral Science 2015; 57: 31-36
149– Kutukculer N, Azarsız E, Karaca NE, Ulusoy E, Koturoğlu G, Aksu G.A clinical and laboratory approach to the evaluation of innate immunity in pediatric CVID patients. Front Immunol. 2015 Apr 27;6:145. doi: 10.3389/fimmu.2015.00145. eCollection 2015.
150-Özdemir Y, Kutukculer N, Topaloğlu A, Kose T, Eronat C. Comporative evaluation of pro-inflammatory cytokine levels in pulpotomized primary molars. Journal of Oral Science 2015; 57; 145-150.
151-Ulusoy E, Karaca NE, El-Shanti H, Kılıcoğlu E, Aksu G, Kutukculer N. Interleukin-1 receptor antagonist deficiency with a novel mutation; late onset and successful treatment with canakinumab; a case report. J Med Case Rep 2015; 9: 145-148.
152-Cavusoğlu C, Karaca NE, Azarsız E, Ulusoy E, Kütükçüler N. Rifampicin-resistant Mycobacterium bovis BCG strain isolated from an infant with NEMO mutation. Mikrobiyol Bul 2015; 49:272-7.
153– Kutukculer N, Azarsız E, Aksu G, Karaca NE. CD4+CD25+Foxp3+ T regulatory cells, Th1 (CCR5, IL-2, IFN-gamma) and Th2 (CCR4, IL-4, IL-13) type chemokine receptors and intracellular cytokines in children with common variable immunodeficiency. Int J Immunopathol Pharmacol 2015;
154–Kutukculer N, Azarsız E, Karaca NE, Aksu G, Berdeli A. Fc gamma receptor poltmorphisms in patients with transient hypogammaglobulinemia of infancy presenting with mild and severe infections. Asian Pac J Allergy Immunol 2015: 33: 312-319.
155-Turkoglu O, Eren G, Emingil G, Azarsız E, Kutukculer N, Atilla G. Does smoking effect gingival crevicular fluid LL-37 levels following non-surgical periodontal treatment in chronic periodontitis? Arch Oral Biol 2016; 61: 98-105.
156-Conti F, Lugo-Reyes SO, Galicia LB, Kutukculer N, et al. Mycobacterial disease in patients with chronic granulomatous diseases: A retrospective analysis of 71 cases. JACI 2016; 138(1):241-248
157-Ulusoy E, Karaca NE, Azarsiz E, Berdeli A, Aksu G, Kutukculer N. Recombinase activating gene 1 deficiencies without Omenn syndrome may also present with eosinophilia and bone marrow fibrosis. J Clin Med Res 2016; 8 (5):
379-84.
158-Türkoğlu O, Emingil G, Eren G, Atmaca H, Kütükçüler N, Atilla G. Gingival crevicular fluid and serum hCAP18/LL-37 levels in generalized aggressive periodontitis. Clin Oral Invest 2017 Apr;21(3):763-769
159-Keleş S, Charbonnier LM, Kabaleeswaran V, Reisli I, Kutukculer N. Dedicator of cytokinesis 8 regulates signal transducer and activator of transciription 3 activation and promotos Th17 cell differentiation. J Allergy Clin Immunol 2016; doi.10.1016
160-Scott EM, Halees A, Itan Y, Spencer EG, Azab MA, Casanova JL, Kutukculer N. Characterization of greater Middle Eastern genetic variation for enhanced disease gene discovery. Nat Genet 2016; July 18;
161-Karaca NE, Aksu G, Ulusoy E, Çavuşoğlu C, Oleaga Quintas C, Nieto-Patlan A, Richard ME, Deswarte C, Casanova JL, Bustamente J, Kutukculer N. Disseminated BCG imfectious disease and hyperferritinemia in a patient with a novel NEMO mutation. J Investig Allergol Clin Immunol 2016: 26 (4); 268-71.
162- Driessen GJ, Wentink M, Trip M, Rizzi M, Çoğulu Ö, Kutukculer N, van der Burg. Increased PI3K/Akt activity and deregulated humoral immune response in human PTEN deficiency. J Allergy Clin Immunol 2016 Agust, doi: 10.1016/j
163- de La Morena MT, Leonard D, Torgerson TR, Slatter M, Kutukculer N, et al. Long term outcomes of 176 patients with X-linked hyper IgM syndrome treated with or without hematopoietic cell transplantation. JACI 2016; sep 30, doi: 10.1016/j.jaci.2016.07.039.
164- Karaca NE, Aksu G, Ulusoy E, Aksoylar s, Kutukculer N. Early diagnosis and hematopetic stem cell transplantation for IL10R deficiency leading to early-onset inflammatory bowel disease are essential in familial cases.Case Reports in Immunology 2016; 2016: 5459029
165– Azarsız E, Karaca NE, Levent E, Kutukculer N, Sözmen E. Chitotriosiadase activity: Is this a possible chronic inflammation marker in children with common variable immunodeficiency and early atherosclerosis. Ann Clin Biochem 2017; pii: 0004563216675647
166- Akarcan SE, Karaca N, Aksu G, Bozkaya H, Kutukculer N, et al. Necrotizing liver granuloma/abscess and contrictive aspergillosis pericarditis with central nervous system involvement: Different remarkable phenotypes in different chronic granulomatous disease genotypes. Case rep Immunol 2017, doi10.1155/2017/2676403.
167-Ulusoy E, Karaca NE, Özen S, Ertan Y, Gökşen D, Aksu G, Darcan Ş, Kütükçüler N. An unusual manifestation: Papillary tiroid carcinoma in a patient with ataxia-telengiectasia. Turk J Pediatr 2016; 58: 442-445.
168-Azarsız E, Karaca N, Ergun B, Durmuşcan M, Kutukculer N, Aksu G. In vitro T lymphocyte proliferation by carboxyfluorescein diacetate succinimidyl ester method is helpful in diagnosing and managing primary immunodeficiencies. J Clin Lab Anal 2017; doi:10.1002/jcla.22216
169-Azarsız E, Karaca NE, Aksu G, Kutukculer N. Reference values for B cell surface markers and co-receptors associated with primary immune deficiencies in healthy Turkish children. Int J Immunopathol Pharmacol 2017; DOİ: 10.1177/
170–Aghamohammadi A, Abolhassani H, Kutukculer N, et al. Patients with Primary Immunodeficiencies are a reservoir for neurovirulent vaccine derived poliovirus strains and represent a risk to the polio eradication initiative. Frontiers in Immunology, doi. 103389/immu 2017
171-Türkoglu O, Emingil G, Eren G, Atmaca H, Kütükçüler N, Atilla G. Levels of LL-37 antimicrobial peptide in the gingivak crevicular fluid of young and middle aged subjects with or without gingivitis. J Istanbul Univ Fac Dent 2017; 51 (1): 15-21.
172-Ulusoy E, Karaca NE, Aksu G, Çavuşoğlu C, Kütükçüler N. Frequency of Mycobacterium bovis and mycobacteria in primary immunodeficiencies. Turkish Archives of Pediatrics 2017; 52: 138-44.
173-Azarsız E, Eman G, Akarcan SE, Severcan EU, Karaca N, Aksu G, Kutukculer N. Anti-Beta2 Glycoprotein I antibodies in Children with Rheumatologic disorders. Ind J Clin Biochem 2017; DOI 10.1007/si2291-017-0711-0.
174-Akarcan SE, Severcan EU, Karaca NE, Işık E, Aksu G, Migaud M, Gurkan FE, Azarsız E, Puel A, Casanova JL, Kutukculer N. Gain-of-function mutations in STAT1: A recently defined cause for chronic mucocutaneous candidiasis disease mimicking combined immune deficiencies. Case Rep Immunol 2017; DOI: 1155/2017/2846928
175-Karaca NE, Ulusoy E, Guven B, Azarsız E, Akarcan S, Gunaydın N, Gülez N, Genel F, Aksu G, Kutukculer N. Familial inheritance and screening of first degree relatives in common variable immunodeficiency and immunoglobulin A deficiency patients. Int J Immunopathol Pharmacol 2018; 32: 1-6.
176- Karaca NE, Severcan EU, Guven B, Azarsiz E, Aksu G, Kutukculer N.
TNFRSF13B/TACI Alterations in Turkish Patients with Common Variable Immunodeficiency and IgA Deficiency. Avicenna J Med Biotechnol. 2018 Jul-Sep;10(3):192-195.
177-Özdemir TR, Karaca NE, Marshall JD, Kutukculer N, Aksu G, Özgül RK, et al. Immunodeficiency in a child with Alström Syndrome. The Indian Journal of Pediatrics 2018; doi.org/10.1007/s12098-018-2740-y
178-Akarcan SE, Karaca NE, Aksu G, Aykut A, Kutukculer N, et al. Two male siblings with a novel LRBA mutation presenting with different findings of IPEX syndrome. JMM Case Reports 2018; 5: Doi 10.1099/jmmcr.005167
179– Kutukculer N, Aykut A, Karaca NE, Durmz A, Aksu G, Genel F, Parıltay E, Çoğulu Ö, Azarsız E. Chronic granulomatous disease: two decades of experience from a pediatric immunology unit in a country with high rate of consanginous marriages.Scand J Immunol 2019 Feb;89(2):e12737. doi: 10.1111/sji.12737. Epub 2019 Jan 23.
180-Azarsız E, Eman G, Akarcan SE, Severcan EU, Karaca N, Aksu G, Kutukculer N. Anti-Beta2 Glycoprotein I antibodies in Children with Rheumatologic disorders. Ind J Clin Biochem 2019 Jan;34(1):95-100. doi: 10.1007/s12291-017-0711-0. Epub 2017 Nov 10.
181-Karaca NE, Aykut A, Parıltay E, Aksu G, Cogulu O, Kutukculer N. A novel TTC37 mutation causing remarkable trichohepatoenteric syndrome clinical findings such as pyoderma gangrenosum and immunodeficiency without severe diarrhea. J Investig Allergol Clin Immunol 2019; doi: 10.18176/jiaci.0418
182– Kutukculer N, Puel A, Akarcan SE, Moriya K, Karaca NE, Migaud M, Casanova JL, Aksu G. DEFICIENCY OF INTERLEUKIN-1 RECEPTOR ANTAGONIST; A CASE WITH LATE ONSET SEVERE INFLAMMATORY ARTHRITIS, NAIL PSORIASIS WITH ONYCHOMYCOSIS AND WELL RESPONSIVE TO ADALIMUMAB NOT TO CANAKINUMAB THERAPY. Case Rep Immunol 2019; doi.org/10.1155/2019/1902817
183-Kıykım A, Oğulur I, Dursun E, Charbonnier LM, Nain E, Kutukculer N. Abatacept as a long term targeted therapy for LRBA deficiency. J Allergy Clin Immunol Pract 2019; doi 10.1016/j.jaip.2019.06.011
184-Karaca N, Azarsız E, Akarcan SE, Aksu G, Kutukculer N. Thymic output changes in children with clinical findings signaling a probable primary immunodeficiency.Turk J Pediatr 2019: 61: 885-894.
185– Tesch VK, Abolhassani H, Shadur B, Zobel J, Mareika Y, Sharapova S, Karakoc-Aydiner E, Rivière JG, Garcia-Prat M, Moes N, Haerynck F, Gonzales-Granado LI, Santos Pérez JL, Mukhina A, Shcherbina A, Aghamohammadi A, Hammarström L, Dogu F, Haskologlu S, İkincioğulları AI, Bal SK, Baris S, Kilic SS, Karaca NE, Kutukculer Net al. Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities evaluated by the immune deficiency and dysregulation activity (IDDA) score. JACI J Allergy Clin Immunol. 2020: 145(5): 1452-63. pii: S0091-6749(19)32603-X. doi: 10.1016/j.jaci.2019.12.896
186-Akarcan SE, Doğantan S, Karaca NE, Aksu G, Kutukculer N. Successful management of colchicine resistant familial Mediterranean fever patients with standardized canakinumab treatment protocol: a case series and literature review. Rhumatol Int 2020; 40(1): 161-69. doi.org/10.1007/s00296-019-04266-w.
187-Cekic S, Metin A, Aytekin C, Karaca NE, Baris S, Karali Y,
Kiykim A, Karakoc Aydıner E, Ozen A, Aslan T, Sevinir B, Aksu
G,Kutukculer N, Kilic SS(1). The evaluation of malignancies in Turkish PID patients; a multicenter study. Pediatr Allergy Immunol. 2020 Feb 14. doi: 10.1111/pai.13231.
188- Moriya K, Kadowaki S, Nakano T, Akarcan SE, Kutukculer N, Aksu G, Casanova JL, Puel A, Fukao T. The IL1RN mutation creating the most-upstream premature stop codon is hypomorphic because of a reinitiation of translation. Journal of Clinical Immunology 2020: 40(4): 641-43. doi: 10.1007/s10875-020-00770-1.
189- Turk S, Aydın D, Doğan E, Levent E, Kutukculer N. Periodic fever syndromes: A patient diagnosed with recurrent Kawasaki Disease. Cardiol Young 2020; June 11, 1-3. Doi: 10.1017/s1047951120001444.
190-Ata A, Özen S, Gökşen D, Karaca NE, Aksu G, Kütükçüler N, Onay H, Darcan Ş. A remarkable co-existence of systemic capillary leak syndrome and diabetes in an 11-year-old boy: A case report and review of the literature. Case Rep Immunol 2020; 16: 34-8.
191-Kütükçüler N, Bölük E, Tökmeci N, Karaca NE, Azarsız E, Aksu G, Aykut A. Recurrent infections, neurologic signs, lowserum uric acid levels and lymphopenia in childhood: Purine nükleozide phosphorylase deficiency, an emercency for infants. Türk Pediatr Arch 2020; 55: 320-7.
192–Sarı G, Güven Bilgin B, Yılmaz E, Aytac G, Edeer Karaca N, Aksu G, Kutukculer N. Efficacy and quality of life assesment in the use of subcutaneous immunoglobulin treatment for children with primary immunodeficiency disorder. Eur Ann Allergy Clin Immunol . 2020 Nov 16. doi: 10.23822/EurAnnACI.1764-1489.179.
193-Necil Kutukculer, Thomas Seeholzer, MSc, Thomas J. O’Neill, MSc, Carina Graß, MSc, Ayca Aykut, MD, Neslihan Edeer Karaca, MD, Asude Durmaz, MD, Ozgur Cogulu, MD, Guzide Aksu, MD, Torben Gehring, PhD, Andreas Gewies, PhD, Daniel Krappmann, PhD.Human immune disorder associated with homozygous hypomorphic mutation affecting MALT1B splice variant.JACI DOI: https://doi.org/10.1016/j.jaci.2021.07.034 (JMF)
194-Özen S, Akçal O, Taşkırdı İ, Hacı İA, Karaca NE, Gülez N, Aksu G, Genel F, Kütükçüler N. 22q11.2 deletion syndrome: 20 years of experience from two pediatric immunology units and review of clues for diagnosis and disease management. Allergol Immunopathol (Madr) . 2021 Jan 2;49(1):95-100. doi: 10.15586/ aei.v49i1.24. eCollection 2021
195- Azarsız E, Karaca NE, Karaca E, Aksu G, Genel F, Gülez N,Özen S, Kütükçüler N. Eight years of follow-up experience in children with mendelian susceptibility to mycobacterial disease and review of the literature. Asian Pac J Immunol (JMF) 2021 Feb 21. doi: 10.12932/AP-271219-0726.
196-Yıldırım İ, Topyıldız E, Bilgin RBY, Aykut A, Durmaz A, Karaca NE, Aksu G, Kutukculer N. X-linked agammaglobulinemia: investigation of clinical and laboratory findings, novel gene mutations and prevention of infectie complications in long term follow-up.Am J Clin Exp Immunol 2021; 10 (1): 37-43.
197- Topyıldız E, Karaca NE, Baş İ, Aykut A, Durmaz A, Bilgin RB, Aksu G, Karapınar D, Kutukculer N. A novel homozygous TRNT1 mutation in a child with an early diagnosis of common variable immunodeficiency leading to mild hypogammaglobulinemia and hemolytic anemia. J Pediatr Hematol Oncol 2021; Apr 9, doi…
198–Kutukculer N, Topyıldız E, Berdeli A, Bilgin BG, Aykut A, Durmaz A, Cogulu Ö, Aksu G, Karaca NE. Four diseases, PLAID, APLAID, FCAS3 and CVID and one gene (PHOSPHOLIPASE C, GAMMA-2; PLCG2): Striking clinical phenotypic overlap and difference. Clin Case Rep. 2021 Mar 2;9(4):2023-2031. doi: 10.1002/ccr3.3934
199-Edeer Karaca N, Özek G, Ataseven E, Tökmeci N, Şenol HD, Kıran E, Aykut A, Durmaz A, Aksu G, Aksoylar S, Aydoğdu S, Çetingül N, Kütükçüler N.
Combined immunodeficiency with marginal zone lymphoma due to a novel homozygous mutation in IL21R gene and successful treatment with hematopoietic stem cell transplantation. Pediatric Hematology Oncology 2021 May 8:1-8. doi: 10.1080/08880018.2021.1924326.
200– Thalhammer J, Kindle G, Nieters A, Rusc S, Seppanen MK, Fischer A, Grimbacher B, Edgar D, Bucland M, Maloi N, Eh S, Kutukculer N. Initial pesentingmanifestations in 16486 patients wit inbornerrors of imunity include infections and noninfectious manifestation. JACI; April, 2021.
201–Asghar Aghamohammadi · Nima Rezaei · Reza Yazdani · Samaneh DelavariNecil Kutukculer · Ezgi Topyildiz · Ahmet Ozen · Safa Baris · Elif Karakoc‑Aydiner · Sara Sebnem Kilic · Hulya Kose · Nesrin Gulez · Ferah Genel · Ismail Reisli Consensus Middle East and North Africa Registry on Inborn Errors of Immunity. Journal of Clinical Immunology https://doi.org/10.1007/s10875-021-01053-z
202-Zilelen S, Duecker RP, Woelke S, Donath H, Kreyenberg H, Kutukculer N, et al. Simple measurement of IgA predicts ımmunity and mortality in Ataxia-telangiectasia. J Clin Immunol 2021; doi.org/10.1007/s10875-021-01090-8
203- Erratum: X-linked agammaglobulinemia: investigation of clinical and laboratory findings, novel gene mutations and prevention of infective complications in long-term follow-up. Yıldırım İ, Topyıldız E, Güven Bilgin RB, Aykut A, Durmaz A, Karaca NE, Aksu G, Kutukculer N. Am J Clin Exp Immunol. 2021 Aug 15;10(2):63-64. eCollection 2021.
204-Aykut A, Durmaz A, karaca N, Gülez N, Celmeli F, Öztürk G, Aksu G, Kütükçüler N. Severe Combined immunodeficiencies: Expanding the mutation spectrum in Turkey and identification of 12 novel variants. Scand J Immunol 2022 Mar 18;e13163. doi: 10.1111/sji.13163.
205– Jabara H, Kutukculer N, et al.DOCK8 functions as an adaptor that links TLR-Myd88 signalling to B cell activation. 24 march, 2022, doi.org/10.1038/ni.2305.
206-Çatak MC, Akçam B, Eltan SB, LO Bernice, Ahmet Özen, Kütükçüler N, Safa Barıs. Comparing the levels of CTLA-4 dependent biological defects in patients with LRBA deficiency and CTLA-4 insufficiency. Allergy 2022 May, doi: 10.1111/ all.15331
207- Topyıldız E, Karaca NE, Aygun A, Aykut A, Durmaz A, aksu G, Kutukculer N.
A novel BLNK gene mutation in a four yera-old child presented with late onset of severe infections, high Igm levels and diagnosed and followed as XLA for two years. Case Rep Immunol.16.5.2022.
208- Gunaydin NC, Azarsiz E, Susluer SY, Kutukculer N, Gunduz C, Gulen F, Aksu G, Tanac R, Demir E Immunological changes in cow’s milk allergic patients during oral desensitization: how these differ from spontaneous tolerance development and nonallergic state. Ann Allergy Asthma Immunol. 2022 Jul 29:S1081-1206(22)00614-7. doi: 10.1016/j.anai.2022.07.022.
209-Jamee M, Azizi G, Barıs S, Karakoç Aydıner E, Özen A, Kutukculer N, et al.Clinical, immunological, molecular and therapeutic findings in monogenic immune dysregulation disease: Middle East and North Africa Registry. Clinical Immunology; 2022; 244: 109131
210- Aytaç G, Güven B, Aydın İ, Topyıldız E, Aykut A, Durmaz A, karaca NE, Aksu G, Kutukculer N. A Remarkable Case of Autoimmune Polyendocrinopathy, Candidiasis and Ectodermal Dystrophy Syndrome (APECED) misdiagnosed as Juvenile Idiopathic Arthritis on admission Case Rep. in İmmunol 2023; doi.org10.1155/2023/2363760.
211-Eser HC, Emecen DA, Topyıldız E, Işık E, Karaca NE, Atik T, Aksu G, özkınay F, Kutukculer N. Dual Diagnosis of Trichohepatoenteric syndrome and lipoid proteinosis in a Turkish child. Mol Syndromol 2023; 14(6); 504-508; DOİ: 10.1159/000531408.
212– Taghizade N, Babayeva R, Kara A, Kutukculer N et al. Therapeutic Modalities and Clinical Outcomes in a Large Cohort with LRBA Deficiency and CTLA4 Insufficiency. JACI. Doi.org/10.016/j.jaci.2023.08.004
213-Azarsız E, Karaca N, Kütükçüler N. Mid-regional proadrenomedullin (MR-proADM) levels in primary immunodeficiencies complicated with pulmonary manifestations. Elif. Indian Journal of Clinical Biochemistry sept 2022, doi.org/10.1007/s12291-022-01061-9 (Indian J Clin Biochem)
214- Aygün A, Topyıldız E, Geyik M, Karaca NE, Durmaz A, Aksu G, Aykut A, Kutukculer N. Current genetic defects in common variable immunodeficiency patients on the geography between Europe and Asia: a single center experience.Immunologic Research. https// doi.org/10.1007/s12026-023-09426-9
215-Taşkın RB, Aydın İ, aytaç G, İmamoğlu S, Tucay SC, Bulut İK, Karaca NE, Aksu G, Berdeli A, Kütükçüler N. Analysis of IL-1beta, TGF-beta, IL-5, ACE, PTPN22 gene polymorphisms and gene expression levels in Turkish children with IgA vasculitis. Molecular Biology reports 2023; 51:15. doi.org/10.1007/s11033-023-08944-x
216-Taşkın RB, Topyıldız E, Karaca NE, Aksu G, Karapınar DY, Kutukculer N. Autoimmune cytopenias are highly assoxiated with inborn errors of immunity and they may be the initial presentations in cases without severe infections. Int Arch Allergy Immunol 2023; 1-10, doi.org/10.1159/00053525258
217- Açıcı NE, Topyıldız E, Aygün A, Geyik M, Karaca NE, Aksu G, Kutukculer N. FASCILITATED SUBCUTANEOUS IMMUNOGLOBULIN TREATMENT INCREASES THE QUALITY OF LIFE AND DECREASES THE NUMBER OF INFECTIONS AND HOSPITALIZATIONS IN CHILDREN WITH PRIMARY IMMUNODEFICIENCIES Int Arch Allergy Immunol 2024; January; doi.org/10.1159/000534900.
218-Aykut A, Durmaz A, Karaca N, Gülez N, Genel F, Kütükçüler N, et al. Primary immune regulatory disorders (PIRD): expanding the mutationspectrum in Turkey and identification of sixteen novel variants. Immunologic Research; doi.org/10.11007/s12026-02409477-6.
219- Topyıldız E, Karaca NE, Taşkın B, Aygün A, Bal ZŞ, saz EU, Kurugöl Z, Kütükçüler N, Aksu G. Alterations in B and NK cells highly correlate with disease severity in children with COVID-10. Turk J Med Sci 2023; 1205-1213.
220– Ulman H, Aygün A, Çağlar D, Dökümcü Z, Topyıldız E, Erdener A, Aksu G, Karaca NE, Özcan C, Kütükçüler N. Transient hypogammaglobulinemia of infancy and unclassified syndromic immunodeficiencies are highly common in oesophageal atresia patients. Scand J ımmunol 2023; doi.org/10.1111/13338.
221– Köksal ZG, Elton SB, Topyıldız E, Sezer A,Kutukculer N, Özen A, Aydıner EK, Barış S. MHC class II deficiency: Clinical, immunological and genetic insights in a large multicenter cohort. JACI in Practice, July 2024
222-Karbiener M, Kindle G, Meyts I, Seppanen MRJ, Candotti F, Kutukculer N et al. Clinical efficacy of SARS-COV-2 Omicron-neutralizing antibodies in immunoglobulin preparations for the treatment of agammaglobulinemia in patients with primary antibody deficiency. J Med Virol June, 2024; DOI: 10.1002/jmv.29738
223-Chavoshzadeh Z, Fallah S, Zienali V, Sharafian S, Delavari S, Kutukculer N, et al. Clinical and molecular findings in actin-related inborn errors of immunity: The Middle east and North Africa registry. Frontiers in Genetics 16:1584681. Doi. 103389/fgene2025.1584681.